Advance Pharmacology

Guidelines: Support your responses with scholarly academic references using APA style format. Assigned course reading and online library resources are preferred. Weekly lecture notes are designed as overviews to the topic for the respective week and should not serve as a citation or reference.

In your discussion question response, provide a substantive response that illustrates a well-reasoned and thoughtful response; is factually correct with relevant scholarly citations, references, and examples; demonstrates a clear connection to the readings
In your participation responses to your peers, comments must demonstrate thorough analysis of postings and extend meaningful discussion by building on previous postings.

Don't use plagiarized sources. Get Your Custom Essay on
Advance Pharmacology
Get an essay WRITTEN FOR YOU, Plagiarism free, and by an EXPERT!
Order Essay

Discussion:
Angela is a 54-year-old married woman with three adult children. She has been the office
manager of a small law firm for 20 years and has enjoyed her work until this past year. She has
rheumatoid arthritis with minimal impairment that has been managed well with NSAIDs. She has
been taking conjugated estrogens for 8 years and decided to stop taking them because of her
concern of their risks without sufficient medical benefit. She has tolerated the discontinuation
without difficulty.

Assessment:
At her annual medical checkup appointment, she told her primary care provider that she seemed
to be tired all the time, and she was gaining weight because she had no interest in her usual
exercise activities and had been overeating, not from appetite but out of boredom. She denied
that she and her husband have had marital difficulties beyond the ordinary and she was pleased
with the achievements of her children. She noticed that she has difficulty falling asleep at night
and awakens around 4 a.m. most mornings without her alarm and cannot go back to sleep even
though she still feels tired. She finds little joy in her life but cannot pinpoint any particular
concern. Although she denies suicidal feelings, she does not feel that there is meaning to her life:
“My husband and kids would go on fine if I died and probably wouldn’t miss me that much.”
The primary care provider asks Angela to fill out a Beck’s Depression Scale, which
indicated she has moderate depression.

1. What medication would you first prescribe to this patient?
2. She comes back in 2 weeks and states she has not noticed and change in her mood since starting on the medication. What would be your response?
3. What are the possible problems with the medication you prescribed?
4. How long should you continue the treatment regimen?

THIS IS AN EXAMPLE ABOUT THIS DISCUSSION. THIS WAS DONE BY A CLASSMATE THIS WEEK.

1. What medication would you first prescribe to this patient?

For Angela, an adequate first-line pharmacological treatment is a selective serotonin reuptake inhibitor (SSRI). SSRIs are safe, well-tolerated, and have similar actions and interactions, being sertraline (Zoloft) considerably cheaper (Ng, How, and Ng, 2017). I would prescribe sertraline 50 mg orally once a day (Sertraline, 2020).
2. She comes back in 2 weeks and states she has not noticed and change in her mood since starting on the medication. What would be your response?

According to Sertraline (2020), “the full effects of sertraline may take eight to 12 weeks to develop.” I would advise Angela to keep taking her medication as prescribed while informing her that will not notice an immediate improvement. I will give Angela a full prospective of information about the medication.
3. What are the possible problems with the medication you prescribed?

The spur of energy effect of the first few months of treatment may increase the risk for suicidal thoughts. SSRIs may cause some degree of sexual dysfunction. Sertraline interactions include any medication that affects serotonin, other antidepressants and most psychotropic medications, anticoagulants, anticonvulsants, cardiac medications affecting QT interval, and HIV medications (Sertraline, 2020). According to Ng, How, and Ng (2017) common side effects of SSRIs are “ associated with nausea, vomiting and a potential worsening of anxiety, especially during the first week, which should resolve over time as the body adjusts to the medication.”

4. How long should you continue the treatment regimen?

The goal of pharmacological treatment for depression is complete remission, even though depression is a fluctuating chronic condition that is likely to recur. All antidepressants’ discontinuation should be tapered down to avoid discontinuation symptoms that include gastrointestinal complaints, flu-like symptoms, affective symptoms, or anxiety that will dissipate within 2 weeks. If the symptoms are mild, good information, counseling, and reassurance should be enough until discontinuation symptoms subside (Shelton, 2001). The World Health Organization recommends treatment to be discontinued not before 9 to 12 months after depression remission (Duration of antidepressant treatment, 2012).

References

Ng, C. W., How, C. H., & Ng, Y. P. (2017). Managing depression in primary care. Singapore medical journal, 58(8), 459–466. https://doi.org/10.11622/smedj.2017080

Sertraline. (2020). Drugs.com. Retrieved from https://www.drugs.com/sertraline.html

Shelton R. C. (2001). Steps Following Attainment of Remission: Discontinuation of Antidepressant Therapy. Primary care companion to the Journal of clinical psychiatry, 3(4), 168–174. https://doi.org/10.4088/pcc.v03n0404

Duration of antidepressant treatment. (2012). World Health Organization. Retrieved from https://www.who.int/mental_health/mhgap/evidence/depression/q2/en/

Homework Market
Order a unique copy of this paper
(550 words)

Approximate price: $22

Basic features
  • Free title page and bibliography
  • Unlimited revisions
  • Plagiarism-free guarantee
  • Money-back guarantee
  • 24/7 support
On-demand options
  • Writer’s samples
  • Part-by-part delivery
  • Overnight delivery
  • Copies of used sources
  • Expert Proofreading
Paper format
  • 275 words per page
  • 12 pt Arial/Times New Roman
  • Double line spacing
  • Any citation style (APA, MLA, Chicago/Turabian, Harvard)

Our guarantees

Since all our papers are written from scratch, the papers we submit are plagiarism free and we strictly adhere to lecturer’s instructions. Our writers are highly qualified from all over the world and include graduates and professors from most of the largest and known universities in the world. Once you have assigned us your assignment, we select the most qualified and reliable writer to handle your assignment.

Money-back guarantee

Unlike other writing companies, we encourage clients to draw back their money at any stage of the writing process if they experience any uncertainties with the quality of generated content. However, you will hardly have to make this decision because of our business approach that suits your needs.

Zero-plagiarism guarantee

We have an advanced plagiarism-detection system that flags any work that fails to meet the required academic expectations. Our company thrives in honesty, and as such, you will be guaranteed to achieve a paper that meets your expectations.

Timely delivery of urgent papers

At homeworkpaper.org we have online agents that you can chat with to have your assignment taken care of with the little remaining time. Also, we have professional academic writers who will work on your assignment providing you with a high-quality paper at the same time. We can take care of your urgent assignments in less than 5 hours.

Privacy policy

We uphold confidentiality and privacy through our interactions with clients, an aspect that has enhanced our relationship with prospective customers seeking for assignment help. We do not disclose your information with third-parties; neither do we share your work with any other person apart from you.

We do not offer pre-written essays

We do not resell previously-done tasks delivered to other clients. When we deliver orders to our clients, we safeguard their privacy and confidentiality by ensuring the third party does not access the work. By writing the papers from scratch, we have managed to maintain a certain level of originality, which defines our business model. Our qualified editors proofread all submitted work to eliminate mistakes that can interfere with the credibility of the assignment.

Calculate the price of your order

550 words
We'll send you the first draft for approval by September 11, 2018 at 10:52 AM
Total price:
$26
The price is based on these factors:
Academic level
Number of pages
Urgency